Fungal endophytes associated with Viola odorata Linn. as bioresource for pancreatic lipase inhibitors
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منابع مشابه
Fungal endophytes associated with Viola odorata Linn. as bioresource for pancreatic lipase inhibitors
BACKGROUND As per the recent statistical reports of World Health Organisation (WHO), 13% of total global population is obese. Orlistat remains to be the only drug approved for the long term treatment of obesity. Recent findings highlighted severe adverse effects of orlistat that included hepatotoxicity, gall stones, kidney stones and acute pancreatitis. Therefore, search for new drug is require...
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In the present study the antibacterial activity of extracts and pure constituents of V. odorata was evaluated against Mycobacterium tuberculosis H37Rv and clinical isolate of MDR-TB (M. avium, ATCC 25291). Crude ethanol extract of the plant was fractionated with different solvents to yield respective extracts. The n-hexane and Dichloromethane fractions showing good activity against both strains...
متن کاملPolyphenolic Compounds as Pancreatic Lipase Inhibitors.
Obesity and its associated diseases such as diabetes mellitus and coronary heart diseases are a major challenge for our society. An important target for the treatment of obesity includes the development of inhibitors of nutrient digestion and absorption. Inhibition of pancreatic lipase and the associated reduction of lipid absorption is an attractive approach for the discovery of potent agents....
متن کاملPhytochemical and Pharmacological Potential of Viola Odorata
Sweet violet also known as the Viola odorata, blooms in continental climate conditions in early spring with delicate flowers of attractive scent. It has been traditionally the part of various indigenous preparations and being used to cure respiratory and inflammatory conditions. Present review article is an attempt to cover recent developments in phytochemical and pharmacological potential of d...
متن کاملThin Layer Chromatography and High Pressure Liquid Chromatography Profiling of Plant Extracts of Viola Odorata Linn
Medicinal plant contains matter that can be used for therapeutic reason or which are precursors for the production of useful drugs. Very few and periodic works are there in the literature regarding the phytochemistry and TLC of Viola odorata L. TLC profiling of plant extract gives an idea about the presence of various phytochemicals. Different Rf (Retention factor) value of various phytochemica...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2017
ISSN: 1472-6882
DOI: 10.1186/s12906-017-1893-y